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Been on Prednisone about 6 weeks. I've had muscle fatigue, espec...

Posted at 9:45 AM on Jul 09, 2004 by carolyndd, #5359
Been on Prednisone about 6 weeks. I've had muscle fatigue, especially when its hot out (walking through a parking lot on a 100 degree day takes a little longer than I'd like). One thing I haven't seen mentioned here is that I have lost lean body mass. I had been having my body fat tested by a personal trainer (pinch calipers) before and after I started (30 mg/day for lung restriction (62%)/inflamation/collagen vascular disease/immune mediated lung disease/likely Mixed Connective Tissue Disease/autoimmune disorder). After 1 month on prednisone, despite the fact that I have continued to work out (cardio and resistance), I lost 3 lbs of Lean Body Mass. 3 weeks later I had lost another 3 LBM, and gained 1 lb fat mass. I'm glad to have kept my overall weight down, and my circumference measurements haven't gone up, but there is definately a redistribution of fat. Other side effects moon face, acne, depression, energy swings (up/down). Heart burn, went from 8 hours sleep to 5 1/2 - 6 average, and facial hair growth. The overwhelming hunger (not just being hungary, but eating a full meal and not feeling satiated at all) has subsided for the most part. The drug is not fun. My doctor is now having me start imuran with the hope of lowering/eliminating the prednisone, but imuran has its own side effects. The hardest part is that the doctors don't know what will work, its guess and check...When the side effects overshaddow the initial symptoms, is it worth it?
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