I started taking Ultracet several months ago for pain after knee surgery but found that it also helped my Fybromialgia symptoms. Any initial side effects such as headache, itching or dizziness ceased after the first week. I take 2 pills only in times of extreme discomfort. 1 at a time works fine and I attempt never to take more than 3 a day. I find sleepiness to be a factor only if I am already in bed (which is good as my primary concern from Fybromialgia is insomnia). Overall, this drug has been a God send for me as I think I would have gone quite mad from the extremely extended and painful healing time after the surgey (compounded by the onset of sciatica which even the Ultracet made only marginally bearable). I am fortunatly not disposed to addictions but I am begining to wonder if the continued taking of a narcotic substance (yes - synthetic - but the effects amount to the same thing) is justified. The euphoria associated with even a low dose is very beguiling; it feels better and more positive than any antidepressant I have ever taken and with far fewer side effects as well. What to do...what to do...no 2 doctors will agree on the matter. My GP says NO; my Rumetologist says Yes!