Thanks to everyone for their courage to post their effects. I was tested 4 months ago and found out I was hypothyroid at 27 yrs old. I started on .25mcg and now at .50 daily of levothyroxine. I have developed a horrible skin rash on my neck, chest, shoulders, and upper back. It looks like small blisters/acne, like chickenpox. Ive never had a skin problem till I took the medication. I have consulted with several doctors and they have given me the usual skin creams, etc. but nothing works and its getting worse. It seems to me that no one knows what to do and I am the only one doing an y research on it. Now, I have an appointment with a dermatologist but my pharmacist said that many thyroid medications can have this reaction and there is little to be done to cure it. Yikes!!!