I've been on Advair for years now. I haven't used an inhaler in as many years. I'm 30 and have been on all the usual stuff. Ventolin, Vanceril, Prednisone, Theofolin, etc. and nothing has worked as good as Advair. However, I have side effects just like everyone else here. My feet hurt, I have achey joints, slight weight gain, etc. After reading some stuff here, I'm switching to once a day and making an appt. with the doc to switch. Asthma sucks, but so does getting a chest cold every other month.