I have been on 150mg of Wellbutrin XL for about 4 weeks. I cannot tolerate caffeine at all while taking it. It results in an inability to breath. I feel as if each time I exhale, it is my last breath. Went to the hospital experiencing shortness of breath and chest pain. They could find nothing wrong. On that day, I had 4 cups of coffee. Today I had only 1 and have spent the night struggling to breath. Am starting to wean my way off Wellbutrin. Not being able to breath is scary stuff.