I am 26, and I had my thyroid removed in November 2003 as a result of having thyroid cancer. I have been on Levoxyl ever since. The first few months, I had trouble sleeping and even taking a 5 minute nap during the day would cause me to be unable to sleep at night. In November 2004 (after a year of adjusting my dosage), they said my thyroid levels were at goal. At the time, I was feeling pretty good (sleeping well, feeling healthy and energetic). But the past month or so, I have been extremely tired and quite moody/depressed. I cry a lot - many times for no reason at all. I had my thyroid levels checked a couple weeks ago, and they said htey at at the goal level. I was talking with a family friend today who is a nurse and told her that I have been extremely tired and fatigue easily. She said that she thinks that the thyroid medications do have side effects that we are not always aware are really from that. Let me know if you have found any solutions to the moody/depressed feelings and emotions and the extreme tiredness. Please email me at ****** if you have any solutions! Thanks!