I have been on Levoxyl for several years, and it is the only medication I can't live without. I can give up my oral diabetes meds by going low carb, my allergy meds and suffer the hay fever, but Levoxyl is my friend. My levels are low normal, borderline if you will, but I have had muscle fatigue since I was a teenager. When I started the med, I could climb stairs without aching, style my hair without my arms trembling. My thin hair filled in and though it is fine, it is full of volume. The pharmacy switched me to the new generic and within three months, I was aching, my hair was thinning, I was 35 and felt 88. Switched back to the brand name, and am well again. The only negative is I have to drink a LOT of water to stayhydrated, but have to do that w/ the diabetes anyway. Alot of the sideeffects I'm reading here sound like dehydration problems. The anxieties, the fatigues. If you aren't drinking your 64oz of water a day, try it and see if it helps.