Wow... stumbling on this site is a breath of relief so far. I've only been on Advair a little less than a month but my anxiety and mood swings seem to have shot through the roof and I've been waking up from less and less sleep every day with no explanation for my sudden bout with insomnia. I'm a 29 year old smoker that quit and started taking 100/50 Advair for an allergy asthma compounded with chronic bronchitis but I think this morning's dose will have been my last. Too bad I relapsed on the cigs before I found this site :/