This medication can cause irregular heartbeat and heart palpatations, which I have as a result of its long-term overuse. Its a good med for asthma, but know the effects and make responsible choices about how often you use it. I've had to use it more frequently as allergy season came about and am reaping the conseqeunces of upped usage with a fluttering heart. DO NOT use if you've had a history of ANY heart disease, your doctor should inform you of this.