Well, I am updating my March 20 post. I am finally up to the 100mcg as prescribed months ago. I felt much better for about 1 month but now - UGH. New side effect though... leg cramps. Not just charlie horses, but cramps in both the calf and the thigh. I am taking potassium, calcium, and magnesium supplements. Nothing is working. I have proper hydration. Any suggestions?