I quit taking Effexor 5 months ago. I did it cold turkey. That was the only way I could do it. I have to admit I felt great. I had more energy when I quit than I had in years. I no longer woke up feeling hung over. I have to say though it did get me through some pretty tough times. I lost 20 lbs since I quit taking it so for those of you with the weight gain don't worry, the weight will come off. The only thing I still have is the intense dreams and night sweats. Everything else seems to have gone away.