I have been taking Darvoset for 2 1/2 years for Cushings Disease. This drug has help me live with the pain. It takes the edge off the hard aches and paines from this disease. In the begining it made me sleepy, but now it takes about an hour to hit the pain last about 3 hrs and I am ready to take the next dose. When I have migraine headaches Imetrix did not touch the pain, so I tried 2 Darvosets at once and it help the headache.