I have been taking advair 500 for over a year, breathing better than ever. In the last month, I have developed severe muscle cramps in my legs that are incapcitating as well as gained weight. I did not have problems with advair until now. The leg cramps are so severe I had to be rescued from a swimming pool. Also, the muscle cramps have on two recent occasions resulted in a painful injury to my legs.
I take advair 500 twice a day. I read in the insert from the pharmacy that if you have been taking corticosteroids for a long time you need to be careful about stopping them cold turkey--it is dangerous.
I am glad I ran across this site and confirmed my suspicion about the leg cramps. I will call my allergist Monday and see what she recommends.