Levaquin I was given Levaquin in August 2004 for a sinus infection. I have had joint pain, muscle pain, headaches, and other strange, unexplainable aching. I have had severe aching in my lower back, knees and legs, causing extreme pain to walk or bend. Sometimes it is almost impossible to get out of bed. The pain seems to move around my body. The doctor could not give me any explanation for this. It has been over two years now and I'm not any better, in fact, it is worse. If I try to exercise, walk for any distance, or do any small project, it leaves me in agony the next several days.