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Wellbutrin SR Besides nausea, I also experience a caffeine-like effect from Wellbutrin. I forgot to put that in my last post - I guess I've been taking the pill so long I forgot about this effect. It is not a problem for me unless I take the pill late in the day - then I have trouble falling asleep. I just make sure to take the pill before noon, and then I avoid the insomnia. I do the same with coffee or anything with caffeine in it. So here is my final side effects list, after 3+ yrs of taking the drug: 1. Nausea 2. Insomnia if taken late in the day, caffeine-like effect 3. Appetite suppression (may be temporary?), weight loss 4. Inability to enjoy smoking cigarettes Hope this helps.
Wellbutrin SR Nausea is the only side effect I have noticed after taking 300 mg of Wellbutrin for over three years now. The nausea is worst in the morning, after I take the pill. My stomach feels very acid, like I just drank a pot of coffee with no breakfast. It usually gets better if I eat something, although not always. For the first few years, I also experienced decreased appetite - no complaints there! I lost weight, but this year I regained it. Not sure if the appetite suppression effect wore off, or if this year has just been really stressful for me. I also found it impossible to smoke cigarettes - they tasted nasty. Another good side effect for me. Overall, Wellbutrin has helped me with depression and social anxiety. Best of all, I have absolutely no sexual side effects, unlike with every other antidepressant I have tried.

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