Methotrexate and mood swings

Posted at 11: 0 AM on Jan 04, 2005 by psjp, #1142

I have been on methotrexate for my psoriasis for just over a month now and have been finding that for the two days I'm on it, plus one or two days afterwards that I seem to be going through some strange mood swings. I can't find anything that has this listed as a side effect, but was wondering if others found this happening to themselves while on the medication. Any ideas or thoughts would be great. Thanks

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Reply on 7:49 PM on Aug 13, 2008 by deefischer, #2397

I have also been on Metho for 1 month now and have recently noticed increased irritability! I wasn't sure if it could be the Metho but it seems to be worse the first 3-4 days. I can't find any info on that as a side effect but am due to see Rheum. next week and I will ask him then.

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