Occasional or regular taking of ibuprofen ?

Hello Blanche, There are some drug interactions that you have to consider. When Ibuprofen is taken with Plavix, it MAY cause an increased risk of bleeding. It can also decrease the effectiveness of your blood pressure pill (Diovan). If you plan on taking Ibuprofen on a long term basis, you definitely need to talk to your doctor and see if he/she wants to make any changes to your current medication regimen. Talk to your doctor about wanting to take Ibuprofen. Your doctor can be the best judge of that and can make the final call for you. He/she can also write you a prescription for the 800mg so you don't have to take 4 tablets at once. It is also more economical. Ibuprofen can be really hard on the stomach. The maximum dose you can take daily is 3.2g. If it hurts your stomach, take it with a snack.