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Prednisone

Posted at 2:54 PM on Nov 11, 2007 by 47140, #3828
Does anyone know if extreme dosages of Prednisone can cause renal failure?
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Reply on 9:42 PM on Nov 14, 2007 by emt338127, #687
I have not heard about renal failure but I have heard that it can cause blindness over long time usage.
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Reply on 9:17 PM on Feb 28, 2008 by fatcat, #1265
Of course, everybody reacts differently while take or withdraw. But there are high number of people who react terribly bad!!! Doctors do not want to recognize and discuss this. They just keep silent... Do you know exactly how Prednisone works??? Nobody knows this for sure, even doctors!!! From my personal experience, and despite gradual withdrawal, I developed extremely high blood pressure, weakness, panic attacks, depression! Practically it ruined my normal life! Doctors have no clue how to deal with its devastating side effects. Steroids are not selective. When you take a steroid, the drug infiltrates the nucleus of every single one OF YOUR CELLS AND STARTS MONKEYING AROUND WITH GENES IT FINDS THERE!!! It probably plays with hundreds of genes. And just a small number of these genes control the pain and inflamation associated with inflamatory diseases, so steroids turn many of these genes off which is good thing. However, because steroids sre not selsctive, they also regulate the genes that control kidney, liver, BRAIN, and HEART function - which is not good thing!!! It is likely that steroid treatment plays with other genes, too, including those we do not know about a lot right now...So, Prednosone pervades the entire body, which increases the likelihood of short-term side effects and long-term DAMAGE. My advice is: THINK TWICE BEFORE TAKING PREDNISONE!!!
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