warfarin and ibuprofen

No. Ibuprofen is in the class of medications called NSAIDs. They are structurally similar and have the same effects as aspirin. They have blood-thinning effects on their own, so when coupled with the coumadin, you could become over-anticoagulated. Unless you have been prescribed an NSAID by your doctor (who is aware you are on Coumadin) or are taking an aspirin a day under MD supervision, it's best to avoid all NSAIDs. Best to use Tylenol for mild pain. LB, RPh.