http://www.medications.com/effect/view/16068 I had headaches with prilosec and nexium so I switched to aciphex which is great for my headaches but I still get frequent heartburn which I guess could be a result of my esoph. ulcer which is not yet healed. I have chapped lips, sometimes anal pruritis, pi Wed, 29 Apr 2009 16:10:46 -0400 http://www.medications.com/effect/view/16068?item=19335 ALERT!!! If you have been having any one of these side effects, then AcipHex may be causing nerve damage. -- tingling or numb hands or feet -- confusion / "fuzzy head" -- ringing in the ears -- vision changes -- anxiety -- depression -- apathy http://www.medications.com/effect/view/16068?item=19335