http://www.medications.com/effect/view/23542 I started on Advair 250/50 6/28/07 for continued wheezing, bronchitis problems even though I quit smoking 12/25/06. In mid July I began to have Lt knee pain, the dx from the Dr was "arthritis--you are getting older you know" I was 46 yrs old. I got a cor Thu, 11 Oct 2007 21:11:49 -0400 http://www.medications.com/effect/view/23542?item=2353 Hi, I'm a 37 year old female and had been on the Advair 250/50 for about 2 years and I also have severe leg pain especially at night. In the middle of the night I feel as if my left knee and left elbow is aching so bad and stiffness. I have been off the http://www.medications.com/effect/view/23542?item=2353