http://www.medications.com/effect/view/24666 I started taking NIASPAN last Wednesday night 500mg and on Thurday night I awoke at 330am feeling like I was on FIRE. My whole body was burning and my skin was turning redder and redder by the minute. I jumped in the cold shower and stayed there for 45 min. Mon, 07 Jan 2008 16:32:11 -0500 http://www.medications.com/effect/view/24666?item=3894 Anykind of Niacin, including Niaspan takes some time to get used to. One dose does not predict how you will ultimately adjust. I've been taking Niaspan for six months and have seen my cholesterol fall into the normal range. However, I do get flushing and i http://www.medications.com/effect/view/24666?item=3894