http://www.medications.com/effect/view/25740 I have been on Wellbutrin XL 150mg for 5 days now and have noticed that I am very short with people and experiencing anger. I tend to lash out. Will this go away? Tue, 18 Dec 2007 18:41:43 -0500 http://www.medications.com/effect/view/25740?item=3519 I've been on Wellbutrin 300 for 3 1/2 years, the last 1 1/2 on XL. I have bi-polar disorder with OCD tendencies on top of Chronic Fatigue Syndrome and of all the drugs on the market I like this one the best. No brain shocks, no lethargy, and no impact to http://www.medications.com/effect/view/25740?item=3519 Wed, 26 Dec 2007 16:49:41 -0500 http://www.medications.com/effect/view/25740?item=3625 Just a quick note .. I have been on Wellbutrin for roughly 3 years as well. I was not diagnosed or treated for depression roughly 7 years before that and things got progressively worse. Main symptoms were CHRONIC lethargy and forgetfulness. Never suicid http://www.medications.com/effect/view/25740?item=3625 Wed, 26 Dec 2007 16:57:30 -0500 http://www.medications.com/effect/view/25740?item=3626 Oh yeah .. and I missed your main question ..sorry. I also was horrible at "lashing out" and I believe there is a chemical imbalance that causes this (maybe hormonal? ). It definitely went away 95 percent of the time for me and I have three kids and LOTS http://www.medications.com/effect/view/25740?item=3626