http://www.medications.com/effect/view/2586 Since starting Lotrel in May, 2002 I have in the past 6 months developed severe muscle and joint pain expecially in my legs and ankles. I used to run 3 to 4 miles 5 times a week. I can hardly do two miles walking now. Could this be Lotrel 5/20? Tue, 02 Sep 2008 00:22:17 -0400 http://www.medications.com/effect/view/2586?item=11865 http://www.medications.com/effect/view/2586?item=11865