http://www.medications.com/effect/view/26102 Started on Effexor XR after trying several other antidepressants. Effexor worked the best for me, and I loved it. But the longer I was on it, the worse things became. I started on 37.5 mg, then up to 75mg. Then to 150mg and then 325. By that time, I was com Wed, 09 Jan 2008 00:00:07 -0500 http://www.medications.com/effect/view/26102?item=3931 took Effexor for about 1 1/2 yrs. I tried several time to get off of it and slumped into depression, constant snapping in my ears, nightmares. it was awful. I finally went to a psych nurse practishioner and she put me down to 37.5 mg and then started to in http://www.medications.com/effect/view/26102?item=3931