http://www.medications.com/effect/view/27965 I was prescribed doxycycline for bronchitis/pneumonia and an ear infection. I've been taking 100mg twice a day for four days now. The heartburn started last night, and though I've had mild cases before, this is unbearable. I cough and feel like I'm going to Fri, 28 Mar 2008 10:26:29 -0400 http://www.medications.com/effect/view/27965?item=5984 Hi, I have been taking Doxycycline for a month for Lymes disease. I have not had the reflux, but my doctor gave me a couple rules to prevent it, because it can cause esophogitis. First rule is not to take it after 7pm. The second rule is to not lie down http://www.medications.com/effect/view/27965?item=5984