Doxycycline Hyclate Side Effects: I only took one doxycycline and experienced my bottom lip breakin http://www.medications.com/effect/view/27984 I only took one doxycycline and experienced my bottom lip breaking out, hearburn, itching of the skin, and yeast infection. Luckily I noticed the side effects with just one pill and did not take anymore. This morning the yeast infection is itching like cr You seem to be having minor side effects, so don't worry. some of Thu, 13 Mar 2008 06:17:11 -0400 http://www.medications.com/effect/view/27984?item=5504 You seem to be having minor side effects, so don't worry. some of the major side effects include difficulty in breathing, red blisters, peeling of skin ..e.tc., There are drugs which interact with Doxycycline and increase the intensity of side effects. Her http://www.medications.com/effect/view/27984?item=5504