Lotrel Side Effects: Lotrel 10/40: Cough, headache, light-headed, poor sleep; wake up http://www.medications.com/effect/view/28197 Lotrel 10/40: Cough, headache, light-headed, poor sleep; wake up every couple of hours, wild dreams and endless urination at night. Take this drug and throw it in the river! same side effects put it in the trash try a new bp. Fri, 20 Jun 2008 17:50:52 -0400 http://www.medications.com/effect/view/28197?item=9345 same side effects put it in the trash try a new bp. http://www.medications.com/effect/view/28197?item=9345