Synthroid Side Effects: We all experience similar problems. I think most of it is from fr http://www.medications.com/effect/view/28805 We all experience similar problems. I think most of it is from frustration and is affecting us all mentally. You go to the doctor pay your co pays,blood work,and your prescriptions. Then patiently wait for change for the better. Go back and do it all over a I ahve been on this medicine my whole life. Im always tired, and Mon, 31 Mar 2008 14:21:01 -0400 http://www.medications.com/effect/view/28805?item=6301 I ahve been on this medicine my whole life. Im always tired, and i cant even remember the last time i felt well rested. i also have HOrrible mood swings and body aches, espically around my period. its horrible. http://www.medications.com/effect/view/28805?item=6301