http://www.medications.com/effect/view/29820 Effective after two weeks for some people - not effective for others. Side effects for some people - others do not report side effects. So why does Merck have to grow their market before they have any idea what's going on? This isn't a big group of Tue, 22 Apr 2008 14:57:49 -0400 http://www.medications.com/effect/view/29820?item=7524 When I asked the question regarding how long before those with seasonal allergies got any response from Singulair, I was thinking about this study which shows that those with leukotriene pathogenesis would probably see results right away and those not in http://www.medications.com/effect/view/29820?item=7524 Sun, 27 Apr 2008 12:28:44 -0400 http://www.medications.com/effect/view/29820?item=7659 Leukotriene Modifiers (like Singulair) do not decrease or 'down regulate' mast cells. Mast cells, when activated (usually by an allergen--pollen etc.) release preformed mediators--histamine chief among them. Anti histamines (Zyrtec. Claritin etc) block t http://www.medications.com/effect/view/29820?item=7659 Mon, 28 Apr 2008 08:48:42 -0400 http://www.medications.com/effect/view/29820?item=7689 Joe, Your explanation of leukotriene modifiers sounds just like Merck's PROMOTIONAL materials. I use the word promotional because that's exactly what Merck's marketing department did to the patient and doctor information. The information is selective and http://www.medications.com/effect/view/29820?item=7689