http://www.medications.com/effect/view/29996 A couple of other symptoms I didn't mention before are I still get cold a lot and ibuprofen is my best friend because of all the aches and pains. But running on 3-5 hours of sleep a night with the occasional 7 hours has definitely diminished the quality of Tue, 29 Apr 2008 11:19:14 -0400 http://www.medications.com/effect/view/29996?item=7736 I am not a doctor but it sounds like you are getting too much Synthroid. You may need to have your TSH levels checked again. They can change rapidly (within 3 weeks). My endo was looking for .5 - 1.5 for the TSH. Any lower than that and you are becomin http://www.medications.com/effect/view/29996?item=7736