PredniSONE Side Effects: I had a bee sting and was put on prednisone for 40mg a day for fi http://www.medications.com/effect/view/30953 I had a bee sting and was put on prednisone for 40mg a day for five days.After my first day on it i had major muscle soreness,very sleepy,heart rate threw the roof and bad headaches.decided i wasn't take another dose but now 7 days out i have water retentio Hi, As you weren't on corticosteroids for a long time, so, proba Fri, 30 May 2008 23:30:53 -0400 http://www.medications.com/effect/view/30953?item=8769 Hi, As you weren't on corticosteroids for a long time, so, probably, it'll take anywhere from a few days to a few weeks to recover. Be well, and if at all possible, stay away from prednisone (and other corticosteroids) as their side effects are many and f http://www.medications.com/effect/view/30953?item=8769