http://www.medications.com/effect/view/31471 I have Hashi's and have been on Synthroid for about 2 years. I was recently on 75 mcg and was teetering on the brink of being hypo again so my doctor increased my dosage to 88 mcg last week. Ever since I have been on the new dosage, I have had the worst ins Thu, 26 Jun 2008 18:12:27 -0400 http://www.medications.com/effect/view/31471?item=9560 Sounds like the T4, which is what Synthroid is, is converting to too much Reverse T3, which can be from having high cortisol. And if your cortisol is too high, you are on your way to having adrenal fatigue, which a LOT of T4-only users eventually get since http://www.medications.com/effect/view/31471?item=9560 Sat, 09 Aug 2008 05:54:47 -0400 http://www.medications.com/effect/view/31471?item=10907 It's 3 am and I am right there with ya. I was on 50 mcg and just increased to 75 mcg and can't sleep a wink. I AM going to be complaining to doc ASAP. What's better? Good thyroid levels or good sleep (as I can feel a cold coming on because of the lack ther http://www.medications.com/effect/view/31471?item=10907