http://www.medications.com/effect/view/31944 My Dad is 75 years old has been in and out of the hospital because of exasperations brought on by COPD. He is fine when he gets out of the hospital with 40mg of Prednisone then like many others tapers to 30mg, 20mg then 10mg until he isn't taking any. Then Tue, 01 Jul 2008 18:05:57 -0400 http://www.medications.com/effect/view/31944?item=9697 My mother went through the same thing. She was a very active woman and gradually became less and less active and got sick more often. The prednisone surpresses the immune system and so she would get another bronchial infection which caused more damage to http://www.medications.com/effect/view/31944?item=9697