http://www.medications.com/effect/view/32182 I have been taking Lotrel 5/10 for a while now. I don't really remember how long because I have symptoms of Alzheimer's. But I also take about 15 others meds. It did lower my blood pressure. A couple of months ago my chest started hurting so bad my wife t Wed, 09 Jul 2008 00:28:34 -0400 http://www.medications.com/effect/view/32182?item=9906 This may be due to drug interaction of Lotrel with other 15 medicines you take. http://www.internationaldrugmart.com/lotrel.html In the above mentioned page, you can find the list of drugs that interact with lotrel and worsen the side effects. Find out if http://www.medications.com/effect/view/32182?item=9906