http://www.medications.com/effect/view/32654 I have had my mirena since April of 2006. For the first two years it was the most wonderful thing in the world ( no cramping, spotting or periods). But lately I have been feeling very horrible. I have no desire to do anything. I am very tired, moody, gained Wed, 23 Jul 2008 15:35:02 -0400 http://www.medications.com/effect/view/32654?item=10381 Oh my god. I can't believe I have just stumbled upon all these women talking about the same problems. Feeling chronic fatigue, depression, listlessness, anxiety and insomnia, bloating and loss of a sex drive! I also experience aching muscles, headaches, http://www.medications.com/effect/view/32654?item=10381