Zantac Side Effects: Oops. Side effects I'm having are depression, shortness of breat http://www.medications.com/effect/view/33373 Oops. Side effects I'm having are depression, shortness of breath and extreme fatigue. I am also experiencing depression, shortness of breath and extrem Sun, 28 Sep 2008 23:04:39 -0400 http://www.medications.com/effect/view/33373?item=12859 I am also experiencing depression, shortness of breath and extreme fatigue with this medication. My breasts are also sore and "swollen" as well. I went up almost one cup size! And I am only on day 2...Is anyone else experiencing this? http://www.medications.com/effect/view/33373?item=12859