http://www.medications.com/effect/view/36191 First I am someone who believes in the less drugs a person has to take, the better off they are. I will go days with a headache before I take an asprin. Recently, on Oct 19, 2008 I was prescribed Bactrim DS and Keflex for what DR. said looked like staph i Fri, 29 May 2009 15:42:36 -0400 http://www.medications.com/effect/view/36191?item=20212 I'm so sorry this happened to you! Bactrim is a sulfa-class drug. Sulfa reactions are not all that unusual, and skin reactions are the most common adverse side-effect. Here's a site that talks about what you describe: http://adam.about.com/encyclopedi http://www.medications.com/effect/view/36191?item=20212 Sat, 15 Aug 2009 17:57:36 -0400 http://www.medications.com/effect/view/36191?item=22264 My daughter had Bactrim and suffered a similar reaction. At the time, the doctor said it was common to have a rash with that medicine and since then she has been listed as being allergic to sulfa drugs. I am also allergic, so it is possible that it runs in http://www.medications.com/effect/view/36191?item=22264