http://www.medications.com/effect/view/36288 I have taken Zoloft (100 mg) on and off for about 10 years. It is very effective at reducing depression for me, but it also dramatically reduces my motivation and ability to concentrate. Hence, I am always eager to get off the drug when I feel I am in a s Fri, 30 Jan 2009 02:45:01 -0500 http://www.medications.com/effect/view/36288?item=16562 http://www.medications.com/effect/view/36288?item=16562