http://www.medications.com/effect/view/38650 1 year ago my wife had a severe sinus infection. Her doctor gave her Z-Pak . She took the 5 day doses 1 day later she had a SEIZURE. My wife has no history of seizures. Now im looking for ancers Can Z-PAK cause seizures ?? Sun, 08 Mar 2009 23:50:20 -0400 http://www.medications.com/effect/view/38650?item=17794 I was also put on a Z pak for a sinus infection 3 weeks ago. I had 2 seizures on the day I took the 5th dose. I have no history of seizures and I had been on the Z pak before. I was told by the doctor that it is really rare that the Z pak would cause se http://www.medications.com/effect/view/38650?item=17794