http://www.medications.com/effect/view/39089 I was prescribed Biaxin Extended Release, 500 mg/2x daily for 10 days, for a sinus infection. I am on the 5th day, and feel absolutely horrible. The nausea is CONSTANT, I am very tired, headaches, stomach cramping, bad gas, sleeplessness..the list goes on a Sat, 14 Mar 2009 14:30:40 -0400 http://www.medications.com/effect/view/39089?item=18000 OMG! I have been taking Biaxin for 3 days. Today I started feeling really depressed. I was crying for no reason and couldn't stop. I thought I was the only one. The doc says depression is not a side effect of this medicine. I disagree. I have a constant ru http://www.medications.com/effect/view/39089?item=18000