http://www.medications.com/effect/view/39220 took the drug for only 4 days and ended up with MAJOR hives. My doc said he's never seen this side effect before and even took pictures to share with his collegues. It did get rid of my sinus infection, but what a price to pay. I took prednisone to get r Fri, 13 Mar 2009 16:29:32 -0400 http://www.medications.com/effect/view/39220?item=17960 HI- How long did your hives last? I took Levaquin first week of Jan 09. AFter 5 days I started getting major hives. The itching was indescribable. Anyway I started prednisone a week later. It got rid of the hives, until I tried to go off the prednisone. http://www.medications.com/effect/view/39220?item=17960 Mon, 16 Mar 2009 22:39:09 -0400 http://www.medications.com/effect/view/39220?item=18097 The hives went mostly went away once I took the prednisone. They did not come back after going off the steriods. I do however, have faint scars where the hives were. I am the only one that can see them- but still a subtle reminder of what happened. I t http://www.medications.com/effect/view/39220?item=18097