http://www.medications.com/effect/view/41507 my boyfriend has been on prednisone for 4 years and he is terribly snappy and aggravated all the time and short tempered and does not think that he is... i love him so i deal with it but its getting harder because he dosnt feel this is correct every time i Sat, 16 May 2009 12:18:29 -0400 http://www.medications.com/effect/view/41507?item=19871 This is what I read from the Prednisone "full prescribing info:" "Psychic derangements may appear when corticosteroids are used, ranging from euphoria, insomnia, mood swings, personality changes, and severe depression, to frank psychotic manifestations. http://www.medications.com/effect/view/41507?item=19871 Mon, 18 May 2009 12:30:52 -0400 http://www.medications.com/effect/view/41507?item=19919 I have been taking Prednisone for about 2 years. I have been tappered down finally to 5mg. down from 80 at the start. I experienced everything from terrible mood swings, moon face, buffalo hump, acne, and severe joint pain. I know exactly how it feels to g http://www.medications.com/effect/view/41507?item=19919