http://www.medications.com/effect/view/41970 I've been on Topamax (100 mg 2x per day) for 5 years as mono therapy for epilepsy. I switched over from Depakote which was a *nightmare* and it has been great, no seizures. I've had the pins and needles, diminished vocabulary and memory, and intermittent ey Tue, 23 Jun 2009 13:49:23 -0400 http://www.medications.com/effect/view/41970?item=20885 My left eye twitches occasionally, sometimes for hours (have been on 800mg for nearly 5 years) but then many 'healthy people have twitching eyes. Yes there is some short term memory loss (my spelling is now so much worse, but technology is wonderful when I http://www.medications.com/effect/view/41970?item=20885