Adderall XR Side Effects: adderall XR -is a time released drug. must be taken first thing http://www.medications.com/effect/view/42285 adderall XR -is a time released drug. must be taken first thing when you wake up... the effects thus will start to wear off around 4pm... and complete by 8 or 9pm. basically we piss it out of our system. don't take on weekends. taking less then 20mg is n Less than 10 mg is not a placebo. Trust me. Why would the DOCTORS Wed, 26 Aug 2009 14:38:16 -0400 http://www.medications.com/effect/view/42285?item=22525 Less than 10 mg is not a placebo. Trust me. Why would the DOCTORS prescribe it if it were? http://www.medications.com/effect/view/42285?item=22525