http://www.medications.com/effect/view/42376 Well, my Fiancee (Sandra) started taking Topamax a few months ago. Her side effects have included: loss of energy, tiredness, tingling in the feet, nausea, chest pain, appetite lose, rapid weight loss, and a severe decrease in her sexual drive. The worst Mon, 06 Jul 2009 16:49:19 -0400 http://www.medications.com/effect/view/42376?item=21229 If the effects are that bad, I'd highly recommend confronting her about it. There are several other anti-migraine meds out there that don't have those kinds of effects. Atenolol comes to mind (or anything in that class of drugs). Some people also have g http://www.medications.com/effect/view/42376?item=21229