http://www.medications.com/effect/view/42500 i just started taking niaspan 500mg er. the second week i had tingling on arms and legs and then the burning itching,felt like i was having a heart attack,got a wash cloth wet my face and hands and legs then later got chills i thought i was going to have to Sun, 11 Oct 2009 03:16:22 -0400 http://www.medications.com/effect/view/42500?item=23491 I have been taking 500mg twice a day for 4 years and have had to stop many times due to the unbearable side effects. My Cardiologist told me last year that Abbott might come out with a better version. They did this spring. They improved the ER coating and http://www.medications.com/effect/view/42500?item=23491