http://www.medications.com/effect/view/42516 I had the Mirena inserted almost 2 years ago. Over the past 6 months, I have had horrible joint pain and swelling in my ankles, knees and hands. I have not been able to wear a wedding ring in 4 months. I hurt so bad that I can't sleep and recently I have Tue, 23 Jun 2009 16:41:46 -0400 http://www.medications.com/effect/view/42516?item=20890 hi i've had mine removed for 10 weeks. when i had it in (only for 6 months) i was being tested for lupus, arthritis, had countless blood tests. the only part of which came back abnormal was my esr levels which were raised, which indicates inflamation. sin http://www.medications.com/effect/view/42516?item=20890