http://www.medications.com/effect/view/42668 I am very reluctant to take any medications, but needed something for a sinus infection that wouldn't go away after 2 weeks. Received 10 day dosage. Drug worked to clear it up, but experienced a noticeable oncoming of depression and emotional detachment f Sun, 23 Aug 2009 13:58:27 -0400 http://www.medications.com/effect/view/42668?item=22452 Me too! I've never been depressed in my entire life and amoxicillin made me feel depressed and emotionally detached. I only had a bladder infection before! I wasn't questioning my entire life or vomiting or having diarrhea! Now I have more problems than I http://www.medications.com/effect/view/42668?item=22452