http://www.medications.com/effect/view/42785 Was prescribed DS (Double strength) 800-160 Sulfameth/Trimeth for 7 days/ 2 pills per day to treat a staph infection from a cut. On the last day, I woke up with a swollen gland under my left ear and a red, itchy rash all over my face and arms. Small hives Sat, 18 Jul 2009 17:07:03 -0400 http://www.medications.com/effect/view/42785?item=21643 Omg. The same thing happened to me. I was about 7 days into a 10 day treatment of bactrim when I too woke up with the gland uder my left ear swollen. On the 9th day of treatment I woke up with and itchy rash on parts of my body. It was the worst around http://www.medications.com/effect/view/42785?item=21643